Using antibodies to detect antigens in tissue sections (FFPE and OCT are the most common) or cell smears, immunohistochemistry provides valuable information for diagnosis, prognosis and treatment planning. It is a key component of anatomic pathology ancillary testing and focuses on cell classification to determine the cause of disease.

IHC is most immunohistochemistry services performed on FFPE tissue sections but can also be conducted on frozen and paraffin-embedded tissue, cell suspensions, or in cell cultures. Generally, antibodies are incubated with sections of tissue or cells and then stained using chromogenic or fluorescent techniques to detect bound antigens.

Immunohistochemistry Services: Accurate and Reliable IHC Testing Solutions

Immunohistochemistry is a key tool for diagnosing cancer and other diseases that affect the hematopoietic system. It is most frequently used to identify and characterize leukemias, lymphomas and other hematological malignancies, based on the specific characteristics of individual cellular structures that can be visualized with particular antibody panels.

The immunohistochemistry market continues to grow, fueled by technological advancements and increasing disease prevalence. Innovations such as AI-integrated assays like Roche’s VENTANA TROP2 RxDx and multiplexing innovations allow for a more precise, scalable, and cost-effective approach, cementing the role of IHC in modern diagnostics.